For anyone interested in longevity supplements and healthy aging, it’s almost impossible not to notice the emergence of NMN and NAD+ into the conversation. In fact, in recent years both scientific and wellness communities seem to be positively buzzing about their potential uses and benefits.
NMN (nicotinamide mononucleotide) and NAD+ (nicotinamide adenine dinucleotide) are two key molecules involved in the production of energy and maintaining cellular health. They are often talked about interchangeably which makes understanding their roles and differences a little bit confusing.
In this article, we’ll talk about exactly what NMN and NAD+ do in our bodies and how they differ from each other. Having a deeper understanding about how these two fascinating molecules work can empower us to make informed decisions about our health and wellness practices.
NMN vs. NAD+: key differences and benefits
Understanding the difference between NMN and NAD+ can be really helpful. Rather than blindly picking a supplement based on what a wellness influencer is promoting, knowledge can help us make educated choices based on our unique health goals.
Difference in function
NAD+. Every single cell in our bodies uses NAD+ to function properly. You could almost think of it as cellular fuel. NAD+ is responsible for helping our cells convert the food we eat into energy we can use for movement and metabolic processes. It also helps our bodies to repair damaged cells and DNA. However, without other building block molecules like NMN or NR (nicotinamide ribonucleotide), our bodies cannot simply make more NAD+.
NMN. NMN could be seen as more like a raw ingredient that our bodies convert into the NAD+ our cells use for fuel. By taking NMN supplements, or by eating more NMN containing foods we may be able to support our body to boost NAD+ production.
Availability and supplement form
NAD+ Supplements. Unfortunately, taking NAD+ in pill and powder form doesn’t bring our NAD+ levels up very much. This is because when it’s taken orally, it travels through the digestive system and is broken down by various metabolic processes leading to poor absorption. To make it work most efficiently, NAD+ supplementation often involves fairly complex delivery methods such as intravenous (IV) therapy.
NMN Supplements. NMN is a more stable and bioavailable molecule, which means it’s absorbed better by our bodies. Once it’s in our bloodstream it can be used and converted to NAD+ within our cells. NMN comes in many forms, including capsules and powders, making it fairly easy to incorporate into a daily wellness routine.
Benefits in supplement form
NAD+ Supplements. Because NAD+ works directly in our cells, supplementation may offer faster benefits for cellular repair and energy production. However, because it’s so easily broken down during the digestive process, taking a pill or powder doesn’t raise our NAD+ levels very much. It needs to be administered in a way that enables our cells to use it effectively. IV NAD+ treatments are often recommended for people who want fast results, such as athletes or people recovering from a stressful situation or illness.
NMN Supplements. NMN is considered to be a more stable and convenient way of replenishing NAD+ levels consistently over time. It’s more accessible and affordable to be able to take a supplement rather than having to visit a clinic for an IV NAD+ treatment.
How NMN supports NAD+ and why this matters
When we take an NMN supplement, it goes through a conversion process to become NAD+. This happens naturally inside our cells. A boost in NAD+ levels may help maintain the energy production and repair systems we depend on for staying healthy and feeling vibrant.
Health benefits of replenishing NAD+ via NMN
- Improved Energy Levels. Recent research suggests that NMN raises NAD+ levels and enhances mitochondrial function. By boosting the capacity of the “powerhouses” of our cells, we may experience better energy levels.
- Anti-Aging Potential. By replenishing NAD+ levels, NMN may help reduce inflammation, support DNA repair, and strengthen cells against various stressors. Recent reports suggest that these effects may slow down some of the processes involved in aging.
- Brain and Heart Health. There has been some promising research into the role of NMN as a support for cognitive function and cardiovascular health. It’s thought to help by improving cellular energy, enhancing cell repair functions, and reducing oxidative stress.
The scientific perspective
While the studies on using NMN for NAD+ production are promising, research is still very much ongoing. Many of the investigations have been conducted on animals, or in vitro so we can’t apply the findings directly to humans. There is also a need for large-scale, longitudinal human studies to look into the long-term effects and range of benefits.
Choosing the best NMN supplement
The market is flooded with NMN supplements, all promising to be the best and most effective. So how do we know how to choose the top NMN supplement? The priority should always be on quality and effectiveness so here are a few key factors that can help you make an informed decision:
- Third-Party Testing. Look for products that have been tested by independent laboratories without ties to a particular brand. They will be able to provide a non-biased verification of the purity and potency of a supplement.
- Purity. Source a supplement that contains NMN in its purest form, without unnecessary fillers, additives, or bulking agents.
- Bioavailability. Choose a product that has been designed specifically for easy and maximum absorption.
- Reputable Brands. Rather than being sucked in by influencer marketing, stick to well-known and reputable brands. Companies should have good customer reviews and a robust history of quality control that you can read about online.
Forms of NMN supplements
There are a few different forms of NMN to choose from:
- Capsules. Easy to pop into your mouth, capsules are a convenient and popular choice for anyone with a busy lifestyle.
- Powders. These are great for adding to our smoothies or drinks and offer a level of flexibility around dosage requirements.
- Lozenges. Lozenges are designed to be dissolved in the mouth, allowing for faster absorption through the tiny capillaries in our cheeks, gums and under the tongue.
The options we choose depend entirely on personal preferences and what fits best with our lifestyle and unique health needs.
Conclusion
NAD+ is found in every cell in our bodies and plays a vital role in our cellular health and energy production. However, it does naturally decline as we get older and our bodies can’t make more of it without help from building blocks like NMN.
While NAD+ acts as a direct source of fuel for our cells, NMN serves as a precursor that our bodies can use to convert into NAD+. Each molecule has unique benefits, and understanding the difference can help us to make the most informed choices for our health.
If you are curious about supporting healthy aging, NMN and NAD+ supplements may offer some valuable benefits. Remember that we are all different and our bodies respond to things in different ways. It’s important to align your choices with your unique health needs and always consult a healthcare provider before starting any new supplement.
FAQs
Why is NAD+ so important for health?
NAD+ is an essential molecule found in every cell in our bodies. It’s a key player in energy production, DNA repair and cellular maintenance. Without enough NAD+ our bodies don’t function at the best or most optimal capacity.
Can NMN replace NAD+ supplements directly?
Not exactly. It’s our cells that convert NMN into NAD+. So we can say that while NMN works by replenishing NAD+ levels, it doesn’t replace the NAD+ itself. NAD+ supplements, administered through an IV for example, may act more immediately while NMN helps boost NAD+ over time.
Are NMN and NAD+ supplements safe?
Studies so far suggest that both NMN and NAD+ supplements are generally well tolerated and safe for most people. However, it’s best to consult a healthcare provider to determine the best course of action for your unique health profile.
How long does it take to see benefits?
It’s important to remember that what works for one person might not work for another. We’re all different. Some people notice improved energy and focus within a few weeks of taking NMN or NAD+ supplements. But results may be incredibly varied depending on individual health and lifestyle.